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Ian Roberts Selected Research

Craniocerebral Trauma (Head Injury)

5/2022A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury.
4/2021Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients.
1/2021Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.
7/2020Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results.
1/2020Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach.
1/2018Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
1/2017Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms.
8/2013Mannitol for acute traumatic brain injury.
12/2012Barbiturates for acute traumatic brain injury.
6/2012WITHDRAWN: Antiepileptic drugs for preventing seizures following acute traumatic brain injury.
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Ian Roberts Research Topics

Disease

76Hemorrhage
05/2022 - 09/2003
57Wounds and Injuries (Trauma)
03/2022 - 03/2002
18Traumatic Brain Injuries (Traumatic Brain Injury)
07/2021 - 12/2009
17Craniocerebral Trauma (Head Injury)
05/2022 - 03/2002
10Stroke (Strokes)
10/2021 - 05/2012
10Myocardial Infarction
10/2021 - 05/2012
9Neoplasms (Cancer)
01/2017 - 09/2005
7Seizures (Absence Seizure)
11/2021 - 06/2012
7Infections
01/2020 - 02/2004
6Pulmonary Embolism
10/2021 - 05/2012
6Venous Thrombosis (Deep-Vein Thrombosis)
10/2021 - 05/2012
6Critical Illness (Critically Ill)
01/2018 - 03/2002
5Infarction (Infarctions)
01/2022 - 01/2007
5Thrombosis (Thrombus)
11/2019 - 06/2012
4Surgical Blood Loss
09/2021 - 04/2010
4Burns
02/2013 - 03/2011
3Postpartum Hemorrhage
06/2022 - 01/2020
3Cerebral Hemorrhage
01/2022 - 01/2016
3Sexually Transmitted Diseases (Sexually Transmitted Disease)
01/2020 - 01/2016
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2011 - 05/2010
2Tics (Tic)
03/2022 - 10/2018
2Multiple Trauma (Multiple Injuries)
07/2021 - 11/2020
2Uterine Inertia
01/2020 - 05/2018
2Exsanguination
06/2018 - 12/2014
2Renal Insufficiency (Renal Failure)
01/2018 - 05/2015
2Cardiovascular Diseases (Cardiovascular Disease)
12/2017 - 07/2005
2Myalgia
12/2017 - 11/2016
2Muscular Diseases (Myopathy)
12/2017 - 11/2016
2Shock
05/2015 - 11/2011
2Hypotension (Low Blood Pressure)
12/2012 - 08/2008
2Coma (Comas)
03/2011 - 10/2004
2Carcinogenesis
05/2010 - 10/2008
2Virus Diseases (Viral Diseases)
02/2010 - 07/2009
2Hypoxia (Hypoxemia)
08/2008 - 08/2007
1Brain Concussion (Cerebral Concussion)
05/2022
1Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
01/2022
1Injection Site Reaction
01/2021
1Hematoma
01/2021
1Sepsis (Septicemia)
08/2019
1Paraproteinemias (Monoclonal Gammopathy)
01/2019
1Intracranial Hemorrhages (Intracranial Hemorrhage)
10/2018
1Maternal Death
06/2018
1Placenta Previa
05/2018
1Pruritus (Itching)
01/2018
1Hypersensitivity (Allergy)
01/2018
1Pain (Aches)
12/2017
1Confusion (Bewilderment)
12/2017
1Intracranial Thrombosis (Cerebral Thrombosis)
01/2017
1Diabetes Mellitus
11/2016
1Vascular Diseases (Vascular Disease)
11/2016
1Rhabdomyolysis
11/2016
1Brain Edema (Cerebral Edema)
08/2013

Drug/Important Bio-Agent (IBA)

84Tranexamic Acid (AMCA)FDA Link
06/2022 - 07/2009
23Antifibrinolytic Agents (Antifibrinolytics)IBA
03/2022 - 02/2005
10Pharmaceutical PreparationsIBA
03/2022 - 07/2005
7Adrenal Cortex Hormones (Corticosteroids)IBA
05/2012 - 03/2002
4Colloids (Colloid)IBA
01/2018 - 03/2011
4Proteins (Proteins, Gene)FDA Link
09/2011 - 02/2004
4DNA (Deoxyribonucleic Acid)IBA
08/2011 - 02/2004
4W 12IBA
05/2010 - 02/2004
3Biological ProductsIBA
01/2018 - 09/2006
3AlbuminsIBA
01/2018 - 03/2002
3SmokeIBA
10/2005 - 09/2002
2FibrinIBA
07/2019 - 12/2018
2FibrinolysinFDA Link
07/2019 - 06/2012
2Biomarkers (Surrogate Marker)IBA
10/2018 - 09/2011
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2017 - 11/2016
2Aprotinin (Trasylol)FDA Link
05/2015 - 01/2010
2Human Serum AlbuminFDA LinkGeneric
11/2011 - 03/2002
2MicroRNAs (MicroRNA)IBA
08/2011 - 10/2008
2MethylprednisoloneFDA LinkGeneric
06/2005 - 10/2004
1fibrin fragment D (D-dimer)IBA
01/2021
1Nucleic AcidsIBA
01/2020
1omega-Chloroacetophenone (Mace)IBA
01/2020
1Amyloid (Amyloid Fibrils)IBA
01/2019
1Dextrans (Dextran)FDA Link
01/2018
1LDL CholesterolIBA
11/2016
1Creatine Kinase (Creatine Phosphokinase)IBA
11/2016
1Atorvastatin (Lipitor)FDA Link
11/2016
1Mannitol (Osmitrol)FDA LinkGeneric
08/2013
1BarbituratesIBA
12/2012
1Thiopental (Pentothal)FDA Link
12/2012
1barbituric acid (barbiturate)IBA
12/2012

Therapy/Procedure

15Blood Transfusion (Blood Transfusions)
01/2020 - 07/2009
8Time-to-Treatment
01/2021 - 03/2011
7Therapeutics
01/2021 - 12/2012
7Resuscitation
01/2018 - 09/2003
5Hysterectomy
08/2019 - 07/2009
3Condoms (Condom)
01/2020 - 01/2016
3Critical Care (Surgical Intensive Care)
07/2019 - 05/2011
2Cardiac Rehabilitation
01/2020 - 01/2019
2Secondary Prevention
01/2019 - 11/2016
1RATE protocol
03/2022
1Cesarean Section (Caesarean Section)
01/2020
1Intravenous Administration
01/2020
1Laparotomy
08/2019
1Treatment Delay
01/2018
1Renal Replacement Therapy (Therapies, Renal Replacement)
01/2018
1Erythrocyte Transfusion
06/2014
1Topical Administration
07/2013